An implantable bilayered synthetic dermal matrix designed to facilitate complex wound closure.

NovoSorb® BTM is composed of a 2mm wound-facing biodegradable foam matrix, bonded to a non-biodegradable transparent sealing membrane. Developed for the treatment of full-thickness wounds where the dermal structure has been lost.

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Bioabsorbable synthetic material

Cellular migration throughout the matrix enables collagen production and neovascularisation of a robust neodermis. When ready, the sealing membrane is removed, leaving a vascularised neodermis, ready for closure. The matrix progressively bioabsorbs over time.3

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Open cell matrix

Matrix architecture breaks a macro wound into a series of interconnected micro wounds that the body can readily heal.

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Fenestrated sealing membrane

Physiologically closes the wound during integration, limiting evaporative moisture loss, contraction and risk of infection.1,2

NovoSorb® BTM in Practice

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    NovoSorb BTM is indicated for full or deep partial thickness burns and wounds, surgical and reconstructive wounds and traumatic wounds.

    References

    1. Greenwood JE, Dearman BL. Comparison of a sealed, polymer foam biodegradable temporizing matrix against Integra® dermal regeneration template in a porcine wound model. J Burn Care Res. 2012; 33:163-73.
    2. Dearman BL, Li A, Greenwood JE. Optimization of a polyurethane dermal matrix and experience with a polymer based cultured composite skin. J Burn care Res. 2014; 35(5): 437-48.
    3. Wagstaff MJD, Schmitt BJ, Coghlan P, Finkemeyer JP, Caplash Y, Greenwood JE. A biodegradable polyurethane dermal matrix in reconstruction of free flap donor sites: a pilot study. ePlasty 2015; 15:102–18.
    4. Greenwood JE, Schmitt BJ, Wagstaff MJD. Experience with a synthetic bilayer Biodegradable Temporising Matrix in significant burn injury. Burns Open. 2018;2(1):17-34.
    5. Solanki NS, York B, Gao Y, Baker P, Wong She RB. A consecutive case series of defects reconstructed using NovoSorb® Biodegradable Temporising Matrix: Initial experience and early results. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2020; 73(10):1845–53.
    6. Wagstaff MJD, Salna I, Caplash Y, et al. Use of a biodegradable synthetic dermal matrix in the reconstruction of defects after serial debridement for necrotising fasciitis: A case series. Burns Open 2018; 3: 12–30.
    7. Damkat-Thomas L, Greenwood JE and Wagstaff MJD. A synthetic Biodegradable Temporising Matrix in degloving lower extremity trauma reconstruction: A case report. Plast Reconstr Surg Global Open 2019; 7: e2110.
    8. Data on file.