An implantable bilayered synthetic dermal matrix designed to facilitate complex wound closure.
NovoSorb® BTM is composed of a 2mm wound-facing biodegradable foam matrix, bonded to a non-biodegradable transparent sealing membrane. Developed for the treatment of full-thickness wounds where the dermal structure has been lost.
Bioabsorbable synthetic material
Cellular migration throughout the matrix enables collagen production and neovascularisation of a robust neodermis. When ready, the sealing membrane is removed, leaving a vascularised neodermis, ready for closure. The matrix progressively bioabsorbs over time.3
Open cell matrix
Matrix architecture breaks a macro wound into a series of interconnected micro wounds that the body can readily heal.
Fenestrated sealing membrane
Physiologically closes the wound during integration, limiting evaporative moisture loss, contraction and risk of infection.1,2
Clinical Case Studies
Robust in the presence of infection4,5
Does not act as a food source for infections, often allowing retention while the infection is treated.Read case study
Designed to minimise contracture over functionally important areas and improve cosmesis (uniformity of texture)6
Compared with primary skin grafting.Read case study
Generation of a neodermis over exposed tendons and bones3,4,6
Can offer alternative treatment for complex wounds.Read case study
- Greenwood JE, Dearman BL. Comparison of a sealed, polymer foam biodegradable temporizing matrix against Integra® dermal regeneration template in a porcine wound model. J Burn Care Res. 2012; 33:163-73.
- Dearman BL, Li A, Greenwood JE. Optimization of a polyurethane dermal matrix and experience with a polymer based cultured composite skin. J Burn care Res. 2014; 35(5): 437-48.
- Wagstaff MJD, Schmitt BJ, Coghlan P, Finkemeyer JP, Caplash Y, Greenwood JE. A biodegradable polyurethane dermal matrix in reconstruction of free flap donor sites: a pilot study. ePlasty 2015; 15:102–18.
- Greenwood JE, Schmitt BJ, Wagstaff MJD. Experience with a synthetic bilayer Biodegradable Temporising Matrix in significant burn injury. Burns Open. 2018;2(1):17-34.
- Solanki NS, York B, Gao Y, Baker P, Wong She RB. A consecutive case series of defects reconstructed using NovoSorb® Biodegradable Temporising Matrix: Initial experience and early results. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2020; 73(10):1845–53.
- Wagstaff MJD, Salna I, Caplash Y, et al. Use of a biodegradable synthetic dermal matrix in the reconstruction of defects after serial debridement for necrotising fasciitis: A case series. Burns Open 2018; 3: 12–30.
- Damkat-Thomas L, Greenwood JE and Wagstaff MJD. A synthetic Biodegradable Temporising Matrix in degloving lower extremity trauma reconstruction: A case report. Plast Reconstr Surg Global Open 2019; 7: e2110.
- Data on file.